[2212.10675] There's Plenty of Room Right Here: Biological Systems as Evolved, Overloaded, Multi-scale Machines

The Nugget

  • Biological systems can simultaneously compute multiple functions using the same substrate (referred to as "polycomputing"), akin to a computer but in a more complex and non-linear way. Understanding and leveraging this can revolutionize fields like regenerative medicine and robotics.

Make it stick

  • ๐Ÿง  Biological systems are like multi-functional computers.
  • ๐Ÿ”ฌ Polycomputing is key: one system, many tasks.
  • ๐Ÿ› ๏ธ Think of biological systems as evolved machines with overloaded capabilities.
  • ๐ŸŒฑ Regenerative medicine and robotics could be transformed by understanding polycomputing.

Protocol

  • The study reviews biological and technological examples where the same system executes multiple functions.
  • It emphasizes the need to adopt an observer-dependent, pragmatic view rather than traditional dichotomies.
  • The authors argue for leveraging polycomputing for designing and evolving new systems with overlapped functionalities.
  • Methodology Strength: This is a review paper, meaning it synthesizes existing research rather than conducting new experiments. This provides a broad perspective but may lack the empirical rigor of primary research.

Terminology

  • Polycomputing: The ability of a single system to perform multiple, concurrent computations.
  • Observer-dependent: Analysis and understanding that vary depending on the observer's perspective and context.
  • Computational Materials: Materials that can perform computational functions, often inspired by or applied to biological contexts.
  • Regenerative Medicine: A branch of medicine focused on repairing or regenerating damaged tissues or organs.
  • Meso-scale: A not well-defined scale between macro and micro-scales, often relevant in the context of biological and physical systems.

Key insights

Polycomputing in Biological Systems

  • Biological systems exhibit complex, simultaneous functionality, such as cells that handle metabolism, signaling, and structural roles concurrently.
  • Evolution has honed these abilities, making biological systems efficient and versatile.

Observer-Dependent Framework

  • The paper promotes a shift in perspective toward observer-dependency, suggesting that our interpretations of biological computing should account for the observerโ€™s context and bias.
  • This could help bridge the understanding gaps between quantum/relativistic scales and biological scales.

Implications for Biomedical Fields

  • Insights from polycomputing can lead to breakthroughs in how we approach regenerative medicine, allowing for more sophisticated tissue engineering and repair.
  • It also opens up new possibilities in robotics, where machines could be designed to mimic the multifunctional nature of biological systems.

Key quotes

  • "Living systems perform multiple functions in the same place at the same time; we call this ability polycomputing."
  • "Overloading different functions on the same hardware is an important design principle that helps understand and build both evolved and designed systems."
  • "An observer-centered framework for the computations performed by these systems will improve our understanding of meso-scale events."
This summary contains AI-generated information and may have important inaccuracies or omissions.