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Effect of fruit on glucose control in diabetes mellitus: a meta-analysis of nineteen randomized controlled trials - PMC

One-liner

A meta-analysis reveals that fruit consumption significantly decreases fasting blood glucose in diabetes patients but does not show a significant difference in glycosylated hemoglobin (HbA1c) levels.

Key insights

Understanding the Study

The systematic meta-analysis evaluated nineteen randomized controlled trials (RCTs) with 888 participants to discern the impact of fruit consumption on glucose control in individuals with diabetes mellitus. The study was thorough, following the PRISMA protocol and assessing inclusion based on strict criteria. The data synthesis utilized RevMan 5.4 software and assessed heterogeneity through the I2 value, using mean difference (MD) and 95% confidence interval (CI) for outcome measures.

Key Findings

Fruit consumption led to a significant reduction in fasting blood glucose levels (MD -8.38, 95% CI -12.34 to -4.43), suggesting possible benefits in managing short-term glucose control for those with diabetes. However, it showed no notable effect on the HbA1c levels (MD -0.17), a marker of long-term glycemic control. Subgroup analysis indicated that both fresh and dried fruit contributed to decreased fasting glucose levels.

Implications

The findings support the inclusion of fruit in the diet of individuals with diabetes, provided overall energy intake remains constant. Contrary to the traditional view that fruit intake might exacerbate diabetes due to sugar content, this analysis suggests that moderate fruit consumption is beneficial for managing fasting blood glucose. However, as the study found high heterogeneity in results for HbA1c, the long-term impact of fruit consumption on diabetes control requires further high-quality research.

Key quotes

  1. "Increasing the fruit intake reduced fasting blood glucose concentration."
  2. "Fruit consumption significantly reduced fasting blood glucose concentrations but had no significant effect on Hb1Ac concentrations in people with diabetes."
  3. "Because the monosaccharides in fruits are mainly fructose-based, have a low blood glucose response, and are slow to absorb, the metabolism of fruit does not require the participation of insulin."

Make it stick

  1. Fight with fruit: Including fruits in the diet can help combat high fasting blood sugar levels in diabetes.
  2. Fresh over fears: Fresh and dried fruits positively influence glucose control, challenging the notion that diabetics should avoid fruit due to its sugar content.
  3. Energy equilibrium: Balancing total energy intake allows the inclusion of fruit without adverse effects on glucose control.
This summary contains AI-generated information and may have important inaccuracies or omissions.